Dihydropyridine compounds having 1,4,4-trisubstitution useful as antihypertensive agents
US4742068A · kind A · utility
3Cited by
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13Claims
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Key dates
| Filing date | Jun 9, 1986 |
| Grant date | May 3, 1988 |
| Priority date | — |
| Expiry date | Jun 9, 2006 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D211/82
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Dihydropyridine compounds having 1,4,4-trisubstitution of the following formula (I): ##STR1## wherein R is one of --COR.sup.3, R.sup.3 being a group such as phenyl or benzyl; R.sup.4 where R.sup.4 is a heterocycle; --(CH.sub.2).sub.n NR.sup.5 R.sup.6, with R.sup.5 and R.sup.6 being alkyl or joined to define a ring; or --(CH.sub.2).sub.n COOR.sup.7, with R.sup.7 being alkyl or benzyl. PA0 R.sup.1 and R.sup.2 are alkyl, phenyl or substituted phenyl. The compounds are useful for the treatment of hypertension in mammals, e.g., in humans.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.