Patent · US Expired

2-halomethyl derivatives of 2-amino acids

US4743691A · kind A · utility

9Cited by

2References

14Claims

0Family size

Assignee

Merrell Dow France et Cie · FR

Inventors

Philippe Bey · Cincinnati, US
Michel Jung · Illkirch-Graffenstaden, FR

Key dates

Filing date	Jun 25, 1982
Grant date	May 10, 1988
Priority date	—
Expiry date	Jun 25, 2002

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

2-(Fluoromethyl or chloromethyl)-2,5-diaminopentanoic acid, 2-(fluoromethyl or chloromethyl)-2,6-diaminohexanoic acid, and 2-fluoromethyl-2-amino-5-guanidinopentanoic acid, and certain derivatives thereof, are inhibitors of ornithine decarboxylase. Methods of preparing the compounds and derivatives are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.