Erodible matrix for sustained release bioactive composition
US4744976A · kind A · utility
129Cited by
6References
85Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 14, 1986 |
| Grant date | May 17, 1988 |
| Priority date | — |
| Expiry date | Oct 14, 2006 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2989
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A sustained release composition for releasing a biologically active compound into an aqueous liquid environment comprises the biologically active compound dispersed in a bioerodible matrix, the matrix comprising a mixture of PA1 (a.) 5% to 99.5% by weight of a solid water-dispersible polyether diol having a molecular weight from about 1000 to about 20,000, and PA1 (b.) 95 to 0.5% by weight of an erosion rate modifier component comprising a combination of stearyl alcohol and stearic acid. Dosage forms comprising the erodible matrix are prepared by molding, particularly by injection molding.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.