Novel d-aminoacid transaminase and its use

US4745061A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Werner Aretz · Königstein, DE
• Klaus Sauber · Schwalbach, DE

Key dates

• Filing date: Dec 20, 1985
• Grant date: May 17, 1988
• Expiry date: Dec 20, 2005

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S435/836
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A D-aminoacid transaminase which converts CPC with .DELTA.-keto acids into .DELTA.-ketoadipinyl-7-ACA can be isolated from Bacillus Licheniformis ATCC 9945. This transamination can be applied to other D-amino acids and can also be used for the preparation of D-amino acids from .DELTA.-keto acids. The enzyme is also suitable for resolving racemates of D,L-amino acids and for detection of .DELTA.-keto acids alongside L-amino acids.