Patent · US Expired

1-((A-substituted phenyl-.omega.-substituted piperazinyl)alkenyl) cyclohexanol

US4745191A · kind A · utility

4Cited by
3References
11Claims
0Family size

Assignee

Inventor

Key dates

Filing dateSep 30, 1987
Grant dateMay 17, 1988
Priority date
Expiry dateSep 30, 2007

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D405/12
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The compounds ##STR1## in which R.sup.1 is 3-hydroxy, 4-hydroxy, 3-methoxy, 4-methoxy or 3,4-methylenedioxy; n is 1 or 2; and R.sup.2 is ##STR2## where R.sup.3 is hydrogen, alkoxy of 1 to 6 carbon atoms, halo or trifluoromethyl; or a pharmaceutically acceptable salt thereof possess anxiolytic and antidepressant activity and are useful in treating psychiatric disorders involving anxiety and/or depression.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.