Substituted 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acids

US4748252A · kind A · utility

Assignee

• Amerimas Home Products, Inc. · US

Inventors

• Eckhardt S. Ferdinandi · Princeton, US
• Dominick Mobilio · Plainsboro, US
• Joseph Peter Sabatucci · Collegeville, US
• Leslie G. Humber · Dollard-Des-Ormeaux, CA

Key dates

• Filing date: Jan 28, 1987
• Grant date: May 31, 1988
• Expiry date: Jan 28, 2007

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D491/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Indole derivatives characterized by having a 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid nucleus bearing a substituent in position 1 and 4. The nucleus may be optionally substituted at position 8. The derivatives are useful anti-inflammatory and analgesic agents and methods and chemical intermediates for their preparation are also disclosed.