Process for the preparation of glycosides from glycosyl fluorides

US4749785A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Joachim Thiem · Hamburg, DE
• Wolfram Fritsche-Lang · Bensheim, DE
• Merten Schlingmann · Königstein, DE
• Hans-Matthias Deger · Hofheim, DE
• Matthias Kreuzer · Munster, DE

Key dates

• Filing date: Jul 12, 1985
• Grant date: Jun 7, 1988
• Expiry date: Jul 12, 2005

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07H15/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for the manufacture of glycosides which comprises reacting a protected hexopyranosyl fluoride with an aglycon or a silyl ether thereof in the presence of a metal fluoride of group IV or V of the periodic table, said metal having an atomic number of at least 22 and being present in the fluoride in a higher, stable and non-oxidizing or weekly oxidizing stage.