Patent · US Expired

Fluoro coumarins as antilymphoedema agents

US4749798A · kind A · utility

7Cited by
1References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 13, 1985
Grant dateJun 7, 1988
Priority date
Expiry dateDec 13, 2005

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D311/18
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A compound of the formula ##STR1## wherein hydrogen, fluorine, chlorine or bromine; B is fluorine, or when A is fluorine B may be hydrogen; PA1 R is hydrogen, C.sub.1 -C.sub.8 branched or unbranched alkyl, CH.sub.2 BR, CH.sub.2 Cl or substituted or unsubstituted phenyl; PA1 X is hydrogen, chlorine or bromine; PA1 one of R.sub.1 and R.sub.2 is hydrogen and the other is hydroxy or C.sub.1 -C.sub.7 branched or unbranched alkoxy unsubstituted or substituted by a dialkyl amino group, or R.sub.1 and R.sub.2, taken together with the carbon atom to which they are linked, form the group ##STR2## with the proviso that, when R and X are both hydrogen, ##STR3## is a ##STR4## group, and B is fluorine and A is hydrogen is useful as antilimphoedema agent.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.