Method of making a diastereomeric mixture containing two diastereomeric .alpha.-acyloxy acid esters
US4749811A · kind A · utility
3Cited by
2References
2Claims
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Key dates
| Filing date | Oct 29, 1985 |
| Grant date | Jun 7, 1988 |
| Priority date | — |
| Expiry date | Oct 29, 2005 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/07
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
In the process of hydrocarboxylating an enol acylate with CO and an organic hydroxyl compound to produce an .alpha.-acyloxy acid ester, the improvement comprising using as the organic hydroxyl compound reactant, an organic hydroxyl compound which has a chiral center that is essentially all L or D, thereby producing a reaction mixture having essentially no enantiomeric pairs and containing diastereomeric .alpha.-acyloxy acid esters having two chiral centers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.