Process for increasing the sexual activity of birds and useful domestic mammals and for preparing spermatozoa suitable to their propagation
US4751215A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 15, 1986 |
| Grant date | Jun 14, 1988 |
| Priority date | — |
| Expiry date | Apr 15, 2006 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/13
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a process for increasing the sexual activity of birds and useful domestic mammals and for preparing spermatozoa suitable to their propagation. The process of the invention comprises treating sexually mature male birds or useful domestic mammals at least twice and at most four times with 0.1 to 5 .mu.g/kg of body weight of a compound of the general formula (I), EQU Glp-His-Trp-Ser-Tyr-X.sub.1 -Leu-Arg-Pro-X.sub.4 (I) wherein PA0 X.sub.1 stands for a glycyl group, a natural or synthetic aminoacid or aminoacid derivative of D configuration, an -Asp-Q group of L configuration, wherein Q is attached to the .alpha.-carbonyl moiety of the aspartyl group and represents a C.sub.1-5 alkylamide, an arylamide, a C.sub.1-4 alkoxy or a benzyloxy group; and PA0 X.sub.4 stands for a glycylamide or a C.sub.1-4 alkylamide group, while keeping a pause of at least 30 hours and at most 72 hours between the consecutive treatments. The process of the invention can mainly be used in such large-scale breedings, where artificial insemination is employed but it can be used also for any domestic bird or cought wild-fowl and ornamental bird as well as useful domestic mammal under the c…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.