2,3,4,5-tetrahydro-1H-3-benzazepines and CNS affecting use thereof

US4751222A · kind A · utility

Assignee

• Novo Industri A/S · DK

Inventors

• Claus T. Braestrup · Copenhagen, DK
• Peter Hongaard Andersen · Rang Taché Est, DK
• Poul Borrevang · Copenhagen, DK
• Frederik C. Gr nvald · Hørsholm, DK
• Louis B. Hansen · Rang Taché Est, DK
• Rolf Hohlweg

Key dates

• Filing date: Apr 21, 1986
• Grant date: Jun 14, 1988
• Expiry date: Apr 21, 2006

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D409/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Novel 2,3,4,5-tetrahydro-1H-3-benzazepines which in the 5-position have furyl, thienyl, pyridyl, or ring systems consisting of phenyl ortho condensed with a benzen, cyclohexan, cyclohexen, cyclopentan or cyclopenten ring wherein one of the carbon atoms may be exchanged with oxygen, sulphur or nitrogen, have interesting central nervous system and cardiovascular effects.