1,6-naphthyridine derivatives

US4751228A · kind A · utility

Assignee

• Goedecke GmbH · DE

Inventors

• Jorgen Kleinschroth · Denzlingen, DE
• Karl Mannhardt · Hornberg, DE
• Johannes Hartenstein · Kirchzarten, DE
• Gerhard Satzinger · Denzlingen, DE
• Dieter Muster · Elzach, DE
• Wolfgang Steinbrecher · Gundelfingen, DE
• Bernd Wagner · Denzlingen, DE
• Hartmut Osswald · Völklingen, DE

Key dates

• Filing date: Jan 28, 1987
• Grant date: Jun 14, 1988
• Expiry date: Jan 28, 2007

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides 1,6-naphthyridine derivatives of formula ##STR1## wherein R.sup.1 is an unsubstituted or substituted aromatic or heteroaromatic ring or an unsubstituted or substituted condensed aromatic or heterocyclic ring system, R.sup.2 is a straight-chained or branched alkyl radical containing up to 4 carbon atoms, a benzyl radical or a straight-chained or branched, substituted or unsubstituted aminoalkyl radical containing up to 8 carbon atoms, R.sup.3 is a hydrogen atom, a straight-chained or branched alkyl radical or an alkoxycarbonyl radical, in each case containing up to 4 carbon atoms, R.sup.4 is a straight-chained or branched hydrocarbon radical containing up to 21 carbon atoms, which can also contain oxygen, sulphur, nitrogen or halogen atoms and is optionally substituted by carbocyclic or heterocyclic ring systems, or is an amino, cyano, formyl, halogenomethyl or dihalomethyl radical and R.sup.5 is an alkoxycarbonyl radical or an unsubstituted or substituted carboxamide radical with, in each case, up to 21 carbon atoms which can also contain oxygen, sulphur or nitrogen atoms and is optionally substituted by carbocyclic or heterocyclic ring systems or is …