Method for preparation of azetidinone-1-oxoacetate by oxidation of the corresponding 2-hydroxyacetate
US4751297A · kind A · utility
5Cited by
2References
3Claims
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Key dates
| Filing date | Mar 20, 1987 |
| Grant date | Jun 14, 1988 |
| Priority date | — |
| Expiry date | Mar 20, 2007 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for production of a 2-azetidinone-1-oxoacetate of the formula ##STR1## useful as an intermediate for preparation of 2-SR.sup.2 -substituted-2-penem-3-carboxylate andtibacterial agents; R is a conventional hydroxy protecting group, R.sup.1 is certain carboxy protecting groups and ##STR2## and m and n are each 0, 1 or 2; which comprises contacting a corresponding (2-oxo-1-axetidinyl)-N-2-hydroxyacetate ester of the formula ##STR3## with manganese dioxide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.