Rapid mutation testing system for human cells
US4753874A · kind A · utility
8Cited by
1References
13Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jul 8, 1985 |
| Grant date | Jun 28, 1988 |
| Priority date | — |
| Expiry date | Jul 8, 2005 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5017
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Mutagenic capability is determined by employing a shuttle vector having prokaryotic and eukaryotic origins, a prokaryotic marker an a gene capable of screening or selection in a prokaryote. The method involves introducing the vector into mammalian cells, exposing the cells to the candidate to be tested for mutagenicity for a time sufficient to allow lesions to occur, rescuing the vector by transforming into a prokaryotic host and screening for mutations of the gene.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.