Condensed as-triazine derivatives
US4753938A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 15, 1985 |
| Grant date | Jun 28, 1988 |
| Priority date | — |
| Expiry date | Oct 15, 2005 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to new compounds of the general Formula I ##STR1## and isomers thereof wherein R.sub.1 is C.sub.1-10 alkyl, C.sub.3-6 cycloalkyl or phenyl, naphthyl or phenyl-(C.sub.1-4 alkyl), wherein the aryl ring of the three latter groups may optionally bear one or more halogen, nitro, trifluoromethyl, amino, hydroxy, C.sub.1-4 alkyl and/or C.sub.1-4 alkoxy substituent(s); PA0 R.sub.2 stands for hydrogen, halogen, hydroxy, oxo, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, phenyl or naphthyl, wherein the two latter groups may optionally bear one or more halogen, nitro, trifluoromethyl, amino, hydroxy, C.sub.1-4 alkyl and/or C.sub.1-4 alkoxy substituent(s); PA0 R.sub.3 represents hydrogen, hydroxy or C.sub.1-4 alkoxy; PA0 Z is buta-1,3-dienyl or a group of the general Formula (a) ##STR2## or (b) ##STR3## and X is hydrogen or halogen. The compounds of the general Formula I possess useful pharmacological properties, particularly antidepressant and antiarrhythmial effect.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.