Peptide from amyloid A and antiserum therefor

US4755380A · kind A · utility

Assignee

• Gambro Lumdia AB · SE

Inventors

• Anders Grubb · Lund, SE
• Lennart Ljunggren · Lund, SE
• Helene K. Hansson · Malmö, SE

Key dates

• Filing date: Feb 6, 1986
• Grant date: Jul 5, 1988
• Expiry date: Feb 6, 2006

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K14/4713
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Substantially pure peptides containing amino acid residues occurring in amyloid A protein and serum amyloid A protein are disclosed. The peptide compounds may be natural or synthetically derived. It is a characteristic feature of the peptides, regardless of their origin, that the sum of the hydrophilicity values of the respective amino acid residues is greater than or equal to zero. Moreover, specific antisera to these peptides are disclosed.