2-(fluoroalkyl)-benzimidazoles as inhibitors of 5-lipoxygenase
US4755525A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 17, 1986 |
| Grant date | Jul 5, 1988 |
| Priority date | — |
| Expiry date | Jun 17, 2006 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A compound of the general formula I: ##STR1## or a salt or solvate thereof, in which, R.sup.1 represents hydrogen or a lower alkyl group, PA0 R.sup.2 represents hydrogen, a lower alkyl group, or ##STR2## R.sup.3 represents hydrogen, a lower alkyl group, or ##STR3## R.sup.4 represents a lower alkyl group substituted by one or more fluorine atoms, PA0 R.sup.5 represents hydrogen, halogen or lower alkyl, and PA0 R.sup.6 represents a lower alkyl or a substituted or unsubstituted carbocyclic aryl group. The compounds are useful as inhibitors of 5-lipoxygenase.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.