Propenylamines, pharmaceutical compositions containing them and their use as pharmaceuticals
US4755534A · kind A · utility
23Cited by
3References
7Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Sep 4, 1984 |
| Grant date | Jul 5, 1988 |
| Priority date | — |
| Expiry date | Sep 4, 2004 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D333/58
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A compound of the formula: ##STR1## wherein the double bond is in the trans configuration and R.sub.1 is a radical of formula IIa, ##STR2## R.sub.2, R.sub.3, R.sub.5, R.sub.7 and R.sub.8 are each hydrogen, R.sub.4 is methyl, and PA0 R.sub.6 is a radical of formula IIIa EQU --C.tbd.C--R.sub.11 IIIa where R.sub.11 is n-butyl, tertiary butyl or phenyl or a chemotherapeutically acceptable acid addition salt thereof; processes for their production, their use as pharmaceuticals and pharmaceutical compositions containing them.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.