Phase supports for the partition chromatography of macromolecules, a process for their preparation and their use
US4756834A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 20, 1987 |
| Grant date | Jul 12, 1988 |
| Priority date | — |
| Expiry date | Jul 20, 2007 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/803
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
Phase supports are disclosured for the partition chromatography of macromolecules. The phase supports are composed of non-adsorptive base support particles which are insoluble in the phase system and which have an average particle size within the range from 7 to 2000 .mu.m. The surface of the support particles is coated with a material which is insoluble in the phase system, adheres firmly to the particles and has an affinity for one of the phases of the phase system for the partition chromatography. Also disclosed is a process for the preparation of the phase supports and their use for separating, by partition chromatography, macromolecules, biopolymers, subcellular units and whole cells, particularly in an aqueous polyethylene glycol/dextran two-phase system.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.