Patent · US Expired

Immobilization of biologically active protein on a polymeric fibrous support

US4757014A · kind A · utility

22Cited by
8References
27Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 8, 1985
Grant dateJul 12, 1988
Priority date
Expiry dateNov 8, 2005

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S530/815
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

A composite article is prepared comprising in sequence a fibrous polymeric support which has been subjected to a surface treatment to provide binding sites thereon, a layer of a protein immobilizer compound, and a biologically active protein. The surface treatment comprises coating the support with a 2 to 500 nm thick layer of inorganic oxide or subjecting the support to a plasma treatment. The protein immobilizer can be a polymer or silane-functional compound. The biologically active protein can be the enzyme, catalase, which has use in decomposing hydrogen peroxide when disinfecting contact lenses.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.