In vitro cell culture system
US4757017A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Sep 14, 1984 |
| Grant date | Jul 12, 1988 |
| Priority date | — |
| Expiry date | Sep 14, 2004 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/18
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
In vitro cell culture systems for anchorage-dependent mammalian cells using solid substrates of mitogenic calcium compounds, such as hydroxyapatite and tricalcium phosphate forms of calcium phosphate and calcium carbonate. The calcium solid substrates can be in the form of granules with a particle size of at least 0.050 mm. or in the form of solid bodies and may be either porous or non-porous. Unique features of cells cultured in the stated in vitro cell culture systems include the growth of cells in layers many cells thick, growth of cells that maintain their phenotype and the ability to culture cells for extended periods of time.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.