Ferrioxamine paramagnetic contrast agents for MR imaging
US4758422A · kind A · utility
30Cited by
2References
18Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Feb 6, 1986 |
| Grant date | Jul 19, 1988 |
| Priority date | — |
| Expiry date | Feb 6, 2006 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/24
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
In the NMR imaging of a subject comprising administering to such subject a composition containing an image-modifying effective amount of an image enhancer, permitting the enhancer to move through the subject, and after a time interval taking an NMR image of the subject, the improvement which comprises employing as said enhancer a complex of an oxamine and a polyvalent paramagnetic metal, e.g. ferrioxamine. Novel complexes of trihydroxamic acids, optionally N-acylated, with polyvalent metals other than iron, are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.