Multiclass hybrid interferons
US4758428A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 15, 1985 |
| Grant date | Jul 19, 1988 |
| Priority date | — |
| Expiry date | Jul 15, 2005 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/142
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
New multiclass hybrid interferon polypeptides, their corresponding encoding recombinant DNA molecules and transformed hosts which produce the new interferons are described. The amino acid sequences of these hybrids include at least two different subsequences, one of which has substantial homology with a portion of a first class of interferon (e.g., HuIFN-.alpha.) and the other which has substantial homology with a portion of a second class of interferon (e.g., HuIFN-.beta.). Data indicates the interferon activity of .alpha.-.beta. hybrids may be substantially restricted to either cell growth regulatory activity or antiviral activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.