Patent · US Expired

Method of purifying Factor VIII:C

US4758657A · kind A · utility

30Cited by

4References

5Claims

0Family size

Assignee

Armour Pharmaceutical · US

Inventors

David L. Farb · Doylestown, US
Ricardo H. Landaburu · Mamaroneck, US

Key dates

Filing date	Jul 11, 1985
Grant date	Jul 19, 1988
Priority date	—
Expiry date	Jul 11, 2005

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed is a process for purifying Factor VIII:C in high yield and potency from source material containing Factor VIII:C, Factor VIII:R and other plasma proteins and factors comprising the steps of: adsorbing Factor VIII:C onto a hydrophobic interaction matrix, separating unwanted proteins from Factor VIII:C and eluting Factor VIII:C by a solution containing a surface active agent.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.