Pyrrothine derivatives and pharmaceutical use thereof

US4760077A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Peter Stahl · New York, US
• Hans Seidel · Tutzing, DE
• Herbert von der Eltz · Spaichingen, DE
• Otto-Henning Wilhelms · Weinheim, DE
• Androniki Roesch · Mannheim, DE

Key dates

• Filing date: May 15, 1986
• Grant date: Jul 26, 1988
• Expiry date: May 15, 2006

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12R2001/625
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

There is described the use of pyrrothine derivatives of the general formula I ##STR1## wherein R.sub.1 and R.sub.3 signify hydrogen or methyl, R.sub.2 hydrogen, methyl or an acyl group with 1 to 5 carbon atoms and X and Y signify hydrogen, an equivalent of a physiolgically acceptable cation or together a single bond, for the inhibition of the allergen-induced degranulation of peripheral leukocytes.