Method for the production of 2'-deoxyadenosine compounds
US4760137A · kind A · utility
25Cited by
3References
9Claims
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Key dates
| Filing date | Jan 15, 1987 |
| Grant date | Jul 26, 1988 |
| Priority date | — |
| Expiry date | Jan 15, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/16
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method that is direct and stereospecific is provided for the production of 2'-deoxyadenosine derivatives and related analogs. The method comprises glycosylation of the sodium salt of 2,6-dichloropurine or 6-chloropurine and ammonolysis of the glycosylate to obtain the corresponding 2-chloro-2'-deoxyadenosine or 2'-deoxyadenosine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.