Nitriles
US4760158A · kind A · utility
2Cited by
3References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 9, 1987 |
| Grant date | Jul 26, 1988 |
| Priority date | — |
| Expiry date | Mar 9, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D211/62
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel 3-halo-2,2-disubstituted propanenitriles of formula ##STR1## wherein Z represents bromo or chloro and A, together with the carbon atom to which it is attached, represents a 5,6 or 7 membered saturated carbocyclic or heterocyclic ring, are useful as intermediates for preparing substituted pyrimido[1,2-a]indoles. The intermediates can be prepared by a novel process which comprises condensing a 2,2-disubstituted ethanenitrile with a dihalomethane in the presence of a non-nucleophilic strong base.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.