New conjugates associating, by covalent bond, an enzyme with an antibody, and medicinal associations using the said conjugates
US4762707A · kind A · utility
22Cited by
5References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 21, 1985 |
| Grant date | Aug 9, 1988 |
| Priority date | — |
| Expiry date | May 21, 2005 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N11/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to new immunoenzymic conjugates resulting from a chemical coupling, by covalent bond, of an antibody or a fragment of antibody, which has retained the capacity of recognizing the selected antigen, with an enzyme capable of producing ammonium ions from natural substrates which are well tolerated in higher animal organisms. The invention also relates to a process for the preparation of these conjugates and the medicinal associations of said conjugates with an immunotoxin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.