Live vaccine for bovine babesiosis
US4762711A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 25, 1986 |
| Grant date | Aug 9, 1988 |
| Priority date | — |
| Expiry date | Feb 25, 2006 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K39/018
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A live vaccine for bovine babesiosis comprises viable bovine erythrocytes parasitized with a cloned population of Babesia bovis, the clone strain being fast-growing, avirulent, and producing a mild but immunizing infection when administered. The vaccine is free of slow-growing virulent B. bovis. The clone strain used in the vaccine is prepared from a natural mixture of virulent and avirulent babesia by progressive dilution culturing to obtain cultures containing single parasites, propagating the single parasites under favorable conditions for growth, and selecting a fast-growing avirulent clone line for either in vitro or in vivo propagation to prepare the vaccines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.