4-alkoxy-pyrido[2,3-d]pyrimidine derivatives for treatment of myocardiac ischemia

US4762837A · kind A · utility

Assignee

• Godecke Aktiengesellschaft · DE

Inventors

• Jurgen Kleinschroth · Denzlingen, DE
• Gerhard Satzinger · Denzlingen, DE
• Karl Mannhardt · Hornberg, DE
• Johannes Hartenstein · Kirchzarten, DE
• Hartmut Osswald · Völklingen, DE
• Gunter Weinheimer · Denzlingen, DE
• Edgar Fritschi · Giengen an der Brenz, DE

Key dates

• Filing date: May 29, 1987
• Grant date: Aug 9, 1988
• Expiry date: May 29, 2007

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

4-Alkoxy-pyrido[2,3-d]pyrimidine derivatives are described as well as processes for their preparation. For reason of their vasospasmolytic effects these compounds are mainly indicated for the treatment of cerebral, cardiac, and peripheral vascular diseases such as myocardiac ischemia, cerebral infarction, pulmonary thromboses, as well as in cases of arterioschlerosis and other stenotic disorders. They are therefore valuable agents for combating cardiovascular mortality.