Process for the purification of acarbose with polymers
US4767850A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 29, 1986 |
| Grant date | Aug 30, 1988 |
| Priority date | — |
| Expiry date | May 29, 2006 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2982
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
In the purification of acarbose by contacting an acarbose-containing solution with a cation exchanger to adsorb the acarbose, eluting the ion exchanger and collecting an eluate fraction enriched in purified acarbose, the improvement wherein the cation exchanger is a polymer obtained by polymerizing an aromatic compound possessing at least one vinyl group and at least one hydrophilic monomer in the presence of a solvent for the monomer which is a precipitant for the crosslinked polymer formed, isolating the resistant polymer, and sulphonating the polymer in the presence of a swelling agent for the polymer. The invention gives sharp separation and other processing advantages.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.