Dianhydrohexite derivatives, and their use as pharmaceuticals

US4769379A · kind A · utility

Assignee

• Heinrich Mack Nachf · DE

Inventors

• Matyas Leitold · Biberach, DE
• Peter Stoss · Illertissen, DE

Key dates

• Filing date: Jul 2, 1985
• Grant date: Sep 6, 1988
• Expiry date: Jul 2, 2005

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Dianhydrohexites of the formula ##STR1## wherein R.sup.1 is hydrogen or benzyl, R.sub.2 is alkyl or omega-theophyllin-7-yl-alkyl, and R.sup.1 and R.sub.2 together with the nitrogen atom to which they are attached form a bicyclic group and R.sup.3 is hydrogen, acyl, pyridylcarbonyl, nitro or a hydroxylamino group, are formed by an analogous method and used as pharmaceuticals in the treatment of heart and circulatory diseases.