Method of increasing the dynamic range and sensitivity of a quadrupole ion trap mass spectrometer operating in the chemical ionization mode
US4771172A · kind A · utility
56Cited by
7References
7Claims
0Family size
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Key dates
| Filing date | May 22, 1987 |
| Grant date | Sep 13, 1988 |
| Priority date | — |
| Expiry date | May 22, 2007 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH01J49/4265
- WIPO fieldElectrical machinery, apparatus, energy
- WIPO sectorElectrical engineering
Abstract
A method is disclosed for increasing the dynamic range and sensitivity of a quadrupole ion trap mass spectrometer operating in the chemical ionization mode. Prior to mass analysis, a prescan is performed with the ion trap and the ionization and reaction periods are adjusted to produce enough stored product or analyte ions to generate a good signal-to-noise ratio in the detection of trace amounts of analyte, yet not so many analyte ions that resolution in the mass spectrum is lost. A mass analysis scan is then performed with the ion trap using the ionization and reaction periods predetermined during the prescan.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.