Patent · US Expired

Method for determination of enzyme activity

US4772553A · kind A · utility

10Cited by
4References
21Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 17, 1986
Grant dateSep 20, 1988
Priority date
Expiry dateJun 17, 2006

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2333/976
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

This invention relates to a method for determining an enzyme-, an enzyme inhibitor-, an enzyme activator-, or zymogen-activity, which comprises allowing the enzyme to react with a substrate of the formula ##STR1## (wherein R.sub.1 represents an amino acid of an oligopeptide combined in the form of ester through the C-terminal carboxyl group of said amino acid or oligopeptide and R.sub.2 represents a hydrogen or bromine atom) to hydrolyze the substrate, then allowing the hydrolysis product of the formula ##STR2## to react with a FR-ITR salt [Fast Red-ITR salt (N,N'-diethyl-4-methoxymetanilamide diazonium salt)] to form a pigment, and determining the pigment.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.