1,10-phenanthroline derivatives and use in fluorescence immunoassays
US4772563A · kind A · utility
55Cited by
6References
29Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 8, 1985 |
| Grant date | Sep 20, 1988 |
| Priority date | — |
| Expiry date | Aug 8, 2005 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/805
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
1,10-phenanthroline-2,9-dicarboxylic acid and novel derivatives thereof such as 4,7-diphenyl-1,10-phenanthroline-2,9-dicarboxylic acid and 4,5,9,14-tetraaza-(1,2,3,4)-dibenzanthracene-3,5-dicarboxylic acid can be coupled to proteins through coupling groups to form conjugates which form higly fluorescent chelates in the presence of lanthanide salts. Derivatives of the above acids reactive toward proteins can be readily manufactured by relatively simple synthetic routes, and are useful in fluorescent immunoassay.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.