Immunogenic peptides of human interleukin-1 and the corresponding anti-peptide antibodies
US4772685A · kind A · utility
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Key dates
| Filing date | Oct 2, 1985 |
| Grant date | Sep 20, 1988 |
| Priority date | — |
| Expiry date | Oct 2, 2005 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/141
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Several distinct peptide regions of the secreted form of purified human interleukin-1 species pI 6.8 have been found to exhibit characteristics associated with highly immunogenic protein moieties and are used to produce specific anti-peptide antibodies. The antibodies raised against the individual peptides are specific for the peptide used for their production and for IL-1, pI 6.8. The individual antibodies bind to both the precursor of IL-1, pI 6.8 and the mature or extracellular IL-1, pI 6.8.
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