N.sup..tau. -substituted histidine derivatives
US4772721A · kind A · utility
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4Claims
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Key dates
| Filing date | Jun 20, 1984 |
| Grant date | Sep 20, 1988 |
| Priority date | — |
| Expiry date | Jun 20, 2004 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/0825
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process is disclosed for the preparation of new N.sup..tau. -substituted histidine derivatives of the general formula ##STR1## According to the process, a histidine derivative of the general formula ##STR2## is reacted with phosgene, and the resultant product is then alkylated and thereafter hydrolyzed with an acid. The products obtained by the process are highly useful for preparation of histidine-analogous proteins and enzymes.
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