Erodible matrix for sustained release bioactive composition
US4774074A · kind A · utility
95Cited by
7References
83Claims
0Family size
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Key dates
| Filing date | Oct 14, 1986 |
| Grant date | Sep 27, 1988 |
| Priority date | — |
| Expiry date | Oct 14, 2006 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2989
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A sustained release composition for releasing a biologically active compound into an aqueous liquid environment comprises said biologically active compound dispersed in a bioerodible matrix, the matrix comprising a mixture of PA1 a. 5% to 99.5% by weight of a solid water-dispersible polyether diol having a molecular weight from about 1000 to about 20,000, and PA1 b. 95 to 0.5% by weight of an erosion rate modifier which is an amphiphilic compound insoluble in the aqueous liquid. Dosage forms comprising the erodible matrix are prepared by molding, particularly by injection molding.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.