Process for the purification, solubilization and/or detoxification of protein antigens of bacteria of the Bordetella genus using a carbonate buffer and an acellular anti-whooping cough vaccine
US4774086A · kind A · utility
8Cited by
8References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 15, 1987 |
| Grant date | Sep 27, 1988 |
| Priority date | — |
| Expiry date | Apr 15, 2007 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/822
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for the purification, solubilization and/or detoxification of protein antigens of bacteria of the Bordetella genus involves the use of a carbonate buffer having a pH of 8.3 to 11.6. An acellular anti-whooping cough vaccine containing active principles in this carbonate buffer is also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.