Patent · US Expired

Immobilization of biological material within a polymer matrix

US4774178A · kind A · utility

28Cited by

7References

19Claims

0Family size

Assignee

BAYER HEALTHCARE LLC · DE

Inventors

Peter Egerer · Wuppertal, DE
Wilfried Haese · Rheydt, DE
Hermann Perrey · Krefeld, DE
Gunter Schmidt-Kastner

Key dates

Filing date	Apr 26, 1985
Grant date	Sep 27, 1988
Priority date	—
Expiry date	Apr 26, 2005

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10S530/817
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Biological material such as microorganisms is immobilized by polymerizing in the presence of the biological material a readily soluble polyetherpolyol having some hydroxyl groups esterified with acrylic and/or methacrylic acid and remaining hydroxyl groups reacted with an isocyanate group-containing derivative of an unsaturated carboxylic acid or a polyfunctional isocyanate. Preferably, the isocyanate derivative of an unsaturated carboxylic acid is isocyanatoethyl acrylate, isocyanatoethyl methacrylate of 4-isocyanato-3-methyl-2-butyl-acrylate and the polyfunctional isocyanate is a diisocyanate or polyisocyanate. Beads can be produced by forming droplets in a water-immiscible medium and polymerizing. Polymerization can be carried out under inert gas in the presence of radical initiators or by irradiation with actinic light.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.