Patent · US Expired

Apparatus and method for liquid chromatography

US4775481A · kind A · utility

29Cited by
3References
51Claims
0Family size

Assignee

Inventor

Key dates

Filing dateAug 10, 1987
Grant dateOct 4, 1988
Priority date
Expiry dateAug 10, 2007

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2030/326
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

To stabilize flow rate in a single-stroke, syringe-type high pressure pump at a constant value after turn-on, a control system increases the pump speed until equilibrium conditions are reached and then pumps at the present rate. In one embodiment, the system is operated in a constant pressure mode under the control of a feedback system to a point at which the pressure is estimated to provide the desired flow rate, with feedback being provided from a pressure measurement and from a flow rate measurement. The feedback from the flow measurement is increased logarithmically with the rate of pumping prior to being compared with the pressure error signal and the comparison between the previous error signal and the logarithmic flow rate signal is used to control the speed of pumping.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.