Imidazoquinolinylether derivatives useful as phosphodiesterase and blood aggregation inhibitors
US4775674A · kind A · utility
40Cited by
3References
56Claims
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Key dates
| Filing date | May 23, 1986 |
| Grant date | Oct 4, 1988 |
| Priority date | — |
| Expiry date | May 23, 2006 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel series of 2,3-dihydro-2-oxo-1H-imidazo[4,5-b]quinolinyl ether derivatives of formula ##STR1## wherein R.sub.1 is hydrogen, lower alkly, benzyl; R.sub.2 is hydrogen, halogen, lower alkyl, lower alkoxy; Alk is alkylene; Y is hydroxy and alkanoic or aralkanoic esters thereof, oxo ketone, dialkylamino, carboxylic acid and esters, carboxamides, alkoxy, ethanolamines and cyclic carbamates thereof, tetrazolyl, and optionally substituted phenylsulfonyl. The compounds are cyclic AMP phosphodiesterase inhibitors and are particularly useful as inhibitors of blood platelet aggregation and/or as cardiotonic agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.