Diazonium compounds useful as components for nucleic acid probes
US4775745A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 8, 1986 |
| Grant date | Oct 4, 1988 |
| Priority date | — |
| Expiry date | Dec 8, 2006 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/828
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This invention relates to a diazonium compound of the formula: ##STR1## wherein Z is selected from the group consisting of biotin, an antigen, an antibody, a photoreactive group, a fluorescent group and heavy metal-containing compounds; PA0 X is an alkylene group containing up to 18 carbon atoms in the principle chain and a total of up to 24 carbon atoms or a substituted alkylene group containing up to 18 carbon atoms in the principle chain with substituents selected from the group consisting of solubility-enhancing groups and cleavable --S--S-- containing moieties; PA0 Ar is an unsubstituted or substituted aryl or heteroaryl; and PA0 Y is an anion and n is an integer from 1-3. Such compounds are useful as components for nucleic acid probes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.