6-Amidino-2-naphthyl 4-guanidinobenzoate derivatives and pharmaceutical composition containing them
US4777182A · kind A · utility
3Cited by
4References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 24, 1986 |
| Grant date | Oct 11, 1988 |
| Priority date | — |
| Expiry date | Feb 24, 2006 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D235/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Amidine compounds of formula (I) ##STR1## and the pharmaceutically acceptable acid addition salts thereof are novel and are of use as anti-trypsin, anti-plasmin, anti-kallikrein, anti-thrombin and anti-complement agents which may be administered orally. These amidine compounds can be produced by the reaction between a carboxylic acid compound of formula (II) ##STR2## or a reactive intermediate thereof and 6-amidino-2-naphthol of formula (III) ##STR3## or preferably an acid addition salt thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.