Process for the selective preparation of isosorbide-2-mononitrate from isosorbide-2,5-dinitrate
US4777274A · kind A · utility
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6Claims
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Key dates
| Filing date | Nov 7, 1986 |
| Grant date | Oct 11, 1988 |
| Priority date | — |
| Expiry date | Nov 7, 2006 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D493/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for the preparation of isosorbide-2-mononitrate (I) ##STR1## from isosorbide-2,5-dinitrate (II) ##STR2## The isosorbide-2,5-dinitrate (II) is treated, in a reaction medium consisting of an aqueous organic solvent, with salts of metals of low oxidation state. Isosorbide-2-mononitrate (I) is obtained with high selectivity.
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