Patent · US Expired

Perhydrothiazepine and perhydroazepine derivatives and their therapeutic use

US4778790A · kind A · utility

2Cited by
6References
44Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 3, 1987
Grant dateOct 18, 1988
Priority date
Expiry dateApr 3, 2007

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds of formula (I): ##STR1## (wherein A is an alkylene group substituted by an optionally substituted amino or heterocyclic group and optionally interrupted by an oxygen or sulfur atom, R.sup.2 is various organic groups, B is C.sub.1 -C.sub.2 alkylene and Y is sulfur or methylene) and pharmaceutically acceptable salts and esters thereof are valuable hypotensive agents which may be prepared by a condensation reaction of the corresponding compound having an amino group in place of the group A--CH(COOH)--NH--.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.