Perhydrothiazepine and perhydroazepine derivatives and their therapeutic use
US4778790A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 3, 1987 |
| Grant date | Oct 18, 1988 |
| Priority date | — |
| Expiry date | Apr 3, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of formula (I): ##STR1## (wherein A is an alkylene group substituted by an optionally substituted amino or heterocyclic group and optionally interrupted by an oxygen or sulfur atom, R.sup.2 is various organic groups, B is C.sub.1 -C.sub.2 alkylene and Y is sulfur or methylene) and pharmaceutically acceptable salts and esters thereof are valuable hypotensive agents which may be prepared by a condensation reaction of the corresponding compound having an amino group in place of the group A--CH(COOH)--NH--.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.