Antihypercholesterolemic tri-yne carbonates
US4780311A · kind A · utility
2Cited by
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9Claims
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Key dates
| Filing date | May 26, 1987 |
| Grant date | Oct 25, 1988 |
| Priority date | — |
| Expiry date | May 26, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/335
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The compounds of the following general structural formula (I) ##STR1## wherein R is hydrogen or a pharmaceutically acceptable salt thereof, are .beta.-ketoacyl-coenzyme A thiolase inhibitors and are useful as antihypercholesterolemic agents for the treatment of disease in which the inhibition of cholesterol biosynthesis would be useful, such as arteriosclerosis, hyperlipidemia and familial hypercholesterolemia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.