Novel monoclonal antibodies to human renin and hybridoma cells, processes for their preparation and their applications
US4780401A · kind A · utility
24Cited by
1References
13Claims
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Key dates
| Filing date | Mar 28, 1985 |
| Grant date | Oct 25, 1988 |
| Priority date | — |
| Expiry date | Mar 28, 2005 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/86
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to novel monoclonal antibodies having a high affinity for human renin, derivatives thereof, processes for the preparation of these antibodies and their derivatives, hybridoma cell lines that produce these antibodies, and to processes for the preparation of said hybridoma cells lines. The monoclonal antibodies according to the invention and their derivatives can be used for the qualitative and quantitative determination of human renin and structurally similar renin, for the purification of human renin and structurally similar renin and for the treatment of high blood pressure and cardiac insufficiency.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.