Isoquinoline derivatives
US4782154A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 17, 1987 |
| Grant date | Nov 1, 1988 |
| Priority date | — |
| Expiry date | Jul 17, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P9/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The isoquinoline derivatives represented by the following general formula (I) are useful as cardiotonics having high cardiotonic activity and low toxicity: ##STR1## where R.sub.1 represents a lower C.sub.1 -C.sub.4 alkyl group or cyclopropyl group, PA0 R.sub.2 represents formyl group, lower C.sub.1 -C.sub.4 alkanoyl group and benzoyl group, lower C.sub.1 -C.sub.4 alkyl group, lower C.sub.1 -C.sub.4 alkenyl group, lower C.sub.1 -C.sub.4 hydroxy substituted alkyl group, C.sub.1 -C.sub.4 perfluoroalkyl group and PA0 R.sub.3 represents 4-pyridyl group or 2-pyridyl group respectively, and the therapeutically acceptable salts thereof are also useful as cardiotonics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.