Method for locating, differentiating, and removing neoplasms
US4782840A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 10, 1986 |
| Grant date | Nov 8, 1988 |
| Priority date | — |
| Expiry date | Sep 10, 2006 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B2090/392
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention is addressed to a method for the improved localization, differentiation, and removal of neoplastic tissue in animals. In particular, one aspect of the present invention involves a surgical procedure wherein an animal suspected of containing neoplastic tissue is surgically accessed and the tissue therein examined visually and by palpation for evidence of neoplastic tissue. The improved methodology commences with the administering to the animal of an effective amount of a labelled antibody specific for neoplastic tissue and labelled with a radioactive isotope exhibiting specific photon emissions of energy levels. Next, and importantly, the surgial procedure is delayed for a time interval following said administering for permitting the labelled antibody to preferentially concentrate in any neoplastic tissue present in the animal so as to increase the ratio of photon emissions from neoplastic tissue to background photon emissions in said animal. Thereafter, an operative field of the animal is surgically accessed and tissue within the operative field to be examined for neoplastic tissue has the background photon emission count determined. Once the background photon…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.